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Acetylcysteine, or N-acetylcysteine, commonly abbreviated as NAC, is the N-acetyl derivative of the protein amino acid L-cysteine. NAC is a delivery form of L-cysteine. L-cysteine is hygroscopic and slowly decomposes and oxidizes. NAC is more stable than L-cysteine, and it may be better absorbed. NAC is a reducing agent and has antioxidant activity. It is also a mucolytic and a hepatoprotectant, and it may have anti-apoptotic activity. It is necessary for the formation and healing of the skin. Hair and skin are made up 10-14% cysteine. Our catalyzed formula includes our phytogenic mineral catalyst for enhanced cellular uptake.

Each 5ml contains

N Acetyl Cysteine Phytogenic Mineral Catalyst           (Containing but not limited to B, Ca, Cr, Co, Cu, I, Fe, Li, Mg, Mn, Mo, P, K, Se, Si, Sr, V, Zn)

250mg 100mcg

 
Inactive Ingredients:
Purified water, Organic Vanilla Flavor, Natural Cane Sugar, Potassium Sorbate (0.1%)
 

Pharmacology and Research of Active Ingredients:

• NAC's efficacy in the treatment of acetaminophen overdose is due mainly to its ability to regenerate liver stores of glutathione. NAC is a delivery form of L-cysteine, which serves as a major precursor to the antioxidant glutathione. An overdose of acetaminophen leads to its metabolism to large quantities of N-acetyl-benzoquinoneimine or NABQI in the liver. NABQI depletes hepatic glutathione stores, placing an enormous oxidative stress on the liver, which can lead to hepatic failure and be life-threatening.
• Several studies have indicated that NAC might be helpful in treating chronic obstructive pulmonary disease (COPD). In an open, controlled multicenter study of 169 patients with moderate-to-severe COPD, subjects were randomized to receive standard treatment plus 600 milligrams of NAC once daily or standard therapy alone for a six-month period. Exacerbations of COPD were reduced 41% in the NAC-treated group, compared with the standard therapy-only group. 
• NAC has improved myocardial contraction in an animal model of myocardial ischemia. It has also been shown to inhibit platelet aggregation; and it has lowered lipoprotein (a) levels to a degree not previously achieved by either drugs or diet, according to some researchers. Additionally, some recent clinical studies have demonstrated that intravenous infusion of NAC during thrombolysis is associated with decreased size of infarct and increased rescue of left ventricular function.

• There is some evidence that NAC may have anti-apoptotic activity, particularly in pancreatic beta-cells and nerve cells. This research is still preliminary, but it is believed that the possible anti-apoptotic effect of NAC is due to its antioxidant activity.  NAC is believed to prevent metastasis by inhibiting gelatinase activity of type VI collagenesis.  NAC enhances T-cell function and may acts as a heavy metal chelator.  NAC may serve a regulatory role in the endogenous production lipoic acid.
• As the N-acetyl derivative of the protein amino acid L-cysteine, NAC is involved in conjugation reactions, and is a component of insulin, skin, hair, coenzyme A, heparin, biotin, glucose tolerance factor and metallothienes.
• Phytogenic Mineral Catalyst – Our Polyfloramin™extracts contain up to 72 trace elements for enhanced bioavailability, assimilation and synergy of the active ingredients contained in our N Acetyl Cysteine formula. 

Clinical Applications:

T J Clark’s NAC formula may be beneficial in the prevention and treatment of:

• Acetaminophen poisoning, AIDS, ageing, cancer therapy, chronic bronchitis, ethanol toxicity, heavy metal poisoning, hepatitis B, infertility, lung fibrosis.
• Metastasis, motor neuron disease, Sjorgren’s syndrome, COPD, oxidation and mucous production through smoking and viral myocarditis.
• Hair and skin, insulin production, and increased oxidation states.

Contents: 237ml
Storage: Store below 30 C
Dosage and Administration: 5ml once or twice daily with food. 

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