T J Clark’s catalysed vitamin B12 and folic acid is formulated as a blood tonic and can assist with the maintenance of peripheral circulation. Inflammatory gastric and intestinal disorders in addition to liver dysfunction are common causes of vitamin B12/folate (folic acid) malabsorption and poor tissue delivery. Many tissues are affected by sub clinical deficiency of B12 and folate before the presence of the classical indication of clinical deficiency, macrocytic anaemia. Taken daily for 1-4 months before conception and during pregnancy, our catalysed formula may reduce the risk of neural tube defects.