Glutamic Acid is synthesised from ammonia and alpha ketoglutarate, an immediate in the Krebs cycle. Glutamic acid is the major precursor of the amino acids glutamine, proline, orthinine and arginine. It is also the precursor for glutathione and GABA synthesis. Energy can be synthesised through the oxidation of glutamic acid. Glutamic acid administration causes the release of luteinizing hormone – releasing hormone, protects the liver through enhanced ammonia detoxification and may have a role in modulating opioid receptors.